TY  - JOUR
A1  - Abdo, N 
A1  - Wetmore, B A
A1  - Chappell, G A
A1  - Shea, D 
A1  - Wright, F A
A1  - Rusyn, I 
T1  - In vitro screening for population variability in toxicity of pesticide-containing mixtures.
Y1  - 2015/12/
N1  - R835166
VL  - 85
SP  - 147
EP  - 155
ER  - 


TY  - JOUR
A1  - Abdo, N 
A1  - Xia, M 
A1  - Brown, C C
A1  - Kosyk, O 
A1  - Huang, R 
A1  - Sakamuru, S 
A1  - Zhou, Y H
A1  - Jack, J R
A1  - Gallins, P 
A1  - Xia, K 
A1  - Li, Y 
A1  - Chiu, W A
A1  - Motsinger-Reif, A A
A1  - Austin, C P
A1  - Tice, R R
A1  - Rusyn, I 
A1  - Wright, F A
T1  - Population-based <em>in vitro</em> hazard and concentration-response assessment of chemicals: the 1000 genomes high-throughput screening study.
Y1  - 2015/05/
N1  - R835166
VL  - 123
IS  - 5
SP  - 458
EP  - 466
ER  - 


TY  - JOUR
A1  - Alexander, D L
A1  - Tropsha, A 
A1  - Winkler, D A
T1  - Beware of R2: simple, unambiguous assessment of the prediction accuracy of QSAR and QSPR models.
Y1  - 2015/07/27
N1  - R835166
VL  - 55
IS  - 7
SP  - 1316
EP  - 1322
ER  - 


TY  - JOUR
A1  - Alves, V M
A1  - Muratov, E 
A1  - Fourches, D 
A1  - Strickland, J 
A1  - Kleinstreuer, N 
A1  - Andrade, C H
A1  - Tropsha, A 
T1  - Predicting chemically-induced skin reactions. Part I: QSAR models of skin sensitization and their application to identify potentially hazardous compounds.
Y1  - 2015/04/15
N1  - R833825
N1  - R835166
VL  - 284
IS  - 2
SP  - 262
EP  - 272
ER  - 


TY  - JOUR
A1  - Alves, V M
A1  - Muratov, E 
A1  - Fourches, D 
A1  - Strickland, J 
A1  - Kleinstreuer, N 
A1  - Andrade, C H
A1  - Tropsha, A 
T1  - Predicting chemically-induced skin reactions. Part II: QSAR models of skin permeability and the relationships between skin permeability and skin sensitization.
Y1  - 2015/04/15
N1  - R833825
N1  - R835166
VL  - 284
IS  - 2
SP  - 273
EP  - 280
ER  - 


TY  - JOUR
A1  - Alves, V 
A1  - Muratov, E 
A1  - Capuzzi, S 
A1  - Politi, R 
A1  - Low, Y 
A1  - Braga, R 
A1  - Zakharov, A V
A1  - Sedykh, A 
A1  - Mokshyna, E 
A1  - Farag, S 
A1  - Andrade, C 
A1  - Kuz'min, V 
A1  - Fourches, D 
A1  - Tropsha, A 
T1  - Alarms about structural alerts.
Y1  - 2016/08/21
N1  - R835166
VL  - 18
IS  - 16
SP  - 4348
EP  - 4360
ER  - 


TY  - JOUR
A1  - Berggren, E 
A1  - Amcoff, P 
A1  - Benigni, R 
A1  - Blackburn, K 
A1  - Carney, E 
A1  - Cronin, M 
A1  - Deluyker, H 
A1  - Gautier, F 
A1  - Judson, R S
A1  - Kass, G E
A1  - Keller, D 
A1  - Knight, D 
A1  - Lilienblum, W 
A1  - Mahony, C 
A1  - Rusyn, I 
A1  - Schultz, T 
A1  - Schwarz, M 
A1  - Schuurmann, G 
A1  - White, A 
A1  - Burton, J 
A1  - Lostia, A M
A1  - Munn, S 
A1  - Worth, A 
T1  - Chemical safety assessment using read-across: assessing the use of novel testing methods to strengthen the evidence base for decision making.
Y1  - 2015/12/
N1  - R835166
VL  - 123
IS  - 12
SP  - 1232
EP  - 1240
ER  - 


TY  - JOUR
A1  - Chappell, G 
A1  - Pogribny, I P
A1  - Guyton, K Z
A1  - Rusyn, I 
T1  - Epigenetic alterations induced by genotoxic occupational and environmental human chemical carcinogens: a systematic literature review.
Y1  - 2016/04/
N1  - R835166
VL  - 768
SP  - 27
EP  - 45
ER  - 


TY  - JOUR
A1  - Chiu, W A
A1  - Wright, F A
A1  - Rusyn, I 
T1  - A tiered, Bayesian approach to estimating population variability for regulatory decision-making.
Y1  - 2017/12/
N1  - R835802
N1  - R835166
VL  - 34
IS  - 3
SP  - 377
EP  - 388
ER  - 


TY  - JOUR
A1  - Cote, I 
A1  - Andersen, M E
A1  - Ankley, G T
A1  - Barone, S 
A1  - Birnbaum, L S
A1  - Boekelheide, K 
A1  - Bois, F Y
A1  - Burgoon, L D
A1  - Chiu, W A
A1  - Crawford-Brown, D 
A1  - Crofton, K M
A1  - DeVito, M 
A1  - Devlin, R B
A1  - Edwards, S W
A1  - Guyton, K Z
A1  - Hattis, D 
A1  - Judson, R S
A1  - Knight, D 
A1  - Krewski, D 
A1  - Lambert, J 
A1  - Maull, E A
A1  - Mendrick, D 
A1  - Paoli, G M
A1  - Patel, C J
A1  - Perkins, E J
A1  - Poje, G 
A1  - Portier, C J
A1  - Rusyn, I 
A1  - Schulte, P A
A1  - Simeonov, A 
A1  - Smith, M T
A1  - Thayer, K A
A1  - Thomas, R S
A1  - Thomas, R 
A1  - Tice, R R
A1  - Vandenberg, J J
A1  - Villeneuve, D L
A1  - Wesselkamper, S 
A1  - Whelan, M 
A1  - Whittaker, C 
A1  - White, R 
A1  - Xia, M 
A1  - Yauk, C 
A1  - Zeise, L 
A1  - Zhao, J 
A1  - DeWoskin, R S
T1  - The next generation of risk assessment multi-year study--highlights of findings, applications to risk assessment, and future directions.
Y1  - 2016/04/
N1  - R835802
N1  - R835802C001
N1  - R835166
VL  - 124
IS  - 11
SP  - 1671
EP  - 1682
ER  - 


TY  - JOUR
A1  - Eduati, F 
A1  - Mangravite, L M
A1  - Wang, T 
A1  - Tang, H 
A1  - Bare, J C
A1  - Huang, R 
A1  - Norman, T 
A1  - Kellen, M 
A1  - Menden, M P
A1  - Yang, J 
A1  - Zhan, X 
A1  - Zhong, R 
A1  - Xiao, G 
A1  - Xia, M 
A1  - Abdo, N 
A1  - Kosyk, O 
A1  - NIEHS-NCATS-UNC, D 
A1  - Friend, S 
A1  - Dearry, A 
A1  - Simeonov, A 
A1  - Tice, R R
A1  - Rusyn, I 
A1  - Wright, F A
A1  - Stolovitzky, G 
A1  - Xie, Y 
A1  - Saez-Rodriguez, J 
T1  - Prediction of human population responses to toxic compounds by a collaborative competition.
Y1  - 2015/09/
N1  - R835166
VL  - 33
IS  - 9
SP  - 933
EP  - 940
ER  - 


TY  - JOUR
A1  - Fourches, D 
A1  - Tropsha, A 
T1  - Using graph indices for the analysis and comparison of chemical datasets.
Y1  - 2013/10/
N1  - R835166
VL  - 32
IS  - 9-10
SP  - 827
EP  - 842
ER  - 


TY  - JOUR
A1  - Fourches, D 
A1  - Muratov, E 
A1  - Tropsha, A 
T1  - Curation of chemogenomics data.
Y1  - 2015/08/
N1  - R835166
VL  - 11
IS  - 8
SP  - 535
ER  - 


TY  - JOUR
A1  - Fourches, D 
A1  - Muratov, E 
A1  - Tropsha, A 
T1  - Trust, but verify II: a practical guide to chemogenomics data curation.
Y1  - 2016/07/25
N1  - R835166
VL  - 56
IS  - 7
SP  - 1243
EP  - 1252
ER  - 


TY  - JOUR
A1  - Grimm, F A
A1  - Iwata, Y 
A1  - Sirenko, O 
A1  - Chappell, G A
A1  - Wright, F A
A1  - Reif, D M
A1  - Braisted, J 
A1  - Gerhold, D L
A1  - Yeakley, J M
A1  - Shepard, P 
A1  - Seligmann, B 
A1  - Roy, T 
A1  - Boogaard, P J
A1  - Ketelslegers, H B
A1  - Rohde, A M
A1  - Rusyn, I 
T1  - A chemical-biological similarity-based grouping of complex substances as a prototype approach for evaluating chemical alternatives.
Y1  - 2016/08/21
N1  - R835802
N1  - R835802C001
N1  - R835166
JF  - GREEN CHEMISTRY
J1  - ACS SYM SER
J2  - GREEN CHEM
VL  - 18
IS  - 16
SP  - 4407
EP  - 4419
ER  - 


TY  - JOUR
A1  - Grimm, F A
A1  - Russell, W K
A1  - Luo, Y S
A1  - Iwata, Y 
A1  - Chiu, W A
A1  - Roy, T 
A1  - Boogaard, P J
A1  - Ketelslegers, H B
A1  - Rusyn, I 
T1  - Grouping of petroleum substances as example UVCBs by ion mobility-mass spectrometry to enable chemical composition-based read-across.
Y1  - 2017/06/20
N1  - R835166
VL  - 51
IS  - 12
SP  - 7197
EP  - 7207
ER  - 


TY  - JOUR
A1  - Grimm, F A
A1  - House, J S
A1  - Wilson, M R
A1  - Sirenko, O 
A1  - Iwata, Y 
A1  - Wright, F A
A1  - Ball
N,  
A1  - Rusyn, I 
T1  - Multi-Dimensional in Vitro Bioactivity Profiling for Grouping of Glycol Ethers.
Y1  - 2019/02/
N1  - R835802
N1  - R835802C001
N1  - R835166
JF  - REGULATORY TOXICOLOGY AND PHARMACOLOGY
J1  - REGUL TOXICOL PHARM
J2  - Regulatory Toxicology and Pharmacology
VL  - 101
SP  - 91
EP  - 102
ER  - 


TY  - JOUR
A1  - Iwata, Y 
A1  - Klaren, W D
A1  - Lebakken, C S
A1  - Grimm, F A
A1  - Rusyn, I 
T1  - High-content assay multiplexing for vascular toxicity screening in induced pluripotent stem cell-derived endothelial cells and human umbilical vein endothelial cells
Y1  - 2017/08/
N1  - R835802
N1  - R835166
VL  - 15
IS  - 6
SP  - 267
EP  - 279
PB  - ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES
ER  - 


TY  - JOUR
A1  - Kushman, M E
A1  - Kraft, A D
A1  - Guyton, K Z
A1  - Chiu, W A
A1  - Makris, S L
A1  - Rusyn, I 
T1  - A systematic approach for identifying and presenting mechanistic evidence in human health assessments.
Y1  - 2013/11/
N1  - R835166
VL  - 67
IS  - 2
SP  - 266
EP  - 277
ER  - 


TY  - JOUR
A1  - Linkov, I 
A1  - Massey, O 
A1  - Keisler, J 
A1  - Rusyn, I 
A1  - Hartung, T 
T1  - From &quot;weight of evidence&quot; to quantitative data integration using multicriteria decision analysis and Bayesian methods.
Y1  - 2015//
N1  - R835166
VL  - 32
IS  - 1
SP  - 3
EP  - 8
ER  - 


TY  - JOUR
A1  - Lock, E F
A1  - Abdo, N 
A1  - Huang, R 
A1  - Xia, M 
A1  - Kosyk, O 
A1  - O'Shea, S H
A1  - Zhou, Y H
A1  - Sedykh, A 
A1  - Tropsha, A 
A1  - Austin, C P
A1  - Tice, R R
A1  - Wright, F A
A1  - Rusyn, I 
T1  - Quantitative high-throughput screening for chemical toxicity in a population-based <em>in vitro</em> model.
Y1  - 2012/04/
N1  - R833825
N1  - R835166
VL  - 126
IS  - 2
SP  - 578
EP  - 588
ER  - 


TY  - JOUR
A1  - Low, Y S
A1  - Sedykh, A Y
A1  - Rusyn, I 
A1  - Tropsha, A 
T1  - Integrative approaches for predicting in vivo effects of chemicals from their structural descriptors and the results of short-term biological assays.
Y1  - 2014//
N1  - R833825
N1  - R832720
N1  - R835166
VL  - 14
IS  - 11
SP  - 1356
EP  - 1364
ER  - 


TY  - JOUR
A1  - Low, Y 
A1  - Sedykh, A 
A1  - Fourches, D 
A1  - Golbraikh, A 
A1  - Whelan, M 
A1  - Rusyn, I 
A1  - Tropsha, A 
T1  - Integrative chemical-biological read-across approach for chemical hazard classification.
Y1  - 2013/08/19
N1  - R835166
VL  - 26
IS  - 8
SP  - 1199
EP  - 1208
ER  - 


TY  - JOUR
A1  - Lu, E 
A1  - Grimm, F 
A1  - Rusyn, I 
A1  - De, S 
A1  - De, B 
A1  - Chiu, W 
T1  - Advancing probabilistic risk assessment by integrating human biomonitoring, new approach methods, and Bayesian modeling: A case study with the mycotoxin deoxynivalenol
Y1  - 2023/12/01
N1  - R835802
N1  - R835166
VL  - 182
IS  - 108326
ER  - 


TY  - JOUR
A1  - Mansouri, K 
A1  - Abdelaziz, A 
A1  - Rybacka, A 
A1  - Roncaglioni, A 
A1  - Tropsha, A 
A1  - Varnek, A 
A1  - Zakharov, A 
A1  - Worth, A 
A1  - Richard, A M
A1  - Grulke, C M
A1  - Trisciuzzi, D 
A1  - Fourches, D 
A1  - Horvath, D 
A1  - Benfenati, E 
A1  - Muratov, E 
A1  - Wedebye, E B
A1  - Grisoni, F 
A1  - Mangiatordi, G F
A1  - Incisivo, G M
A1  - Hong, H 
A1  - Ng, H W
A1  - Tetko, I V
A1  - Balabin, I 
A1  - Kancherla, J 
A1  - Shen, J 
A1  - Burton, J 
A1  - Nicklaus, M 
A1  - Cassotti, M 
A1  - Nikolov, N G
A1  - Nicolotti, O 
A1  - Andersson, P L
A1  - Zang, Q 
A1  - Politi, R 
A1  - Beger, R D
A1  - Todeschini, R 
A1  - Huang, R 
A1  - Farag, S 
A1  - Rosenberg, S A
A1  - Slavov, S 
A1  - Hu, X 
A1  - Judson, R S
T1  - CERAPP: Collaborative Estrogen Receptor Activity Prediction Project.
Y1  - 2016/07/
N1  - R835166
JF  - ENVIRONMENTAL HEALTH PERSPECTIVES
J1  - ENVIRON HEALTH PERSP
J2  - Environ.Health Perspect.
J3  - Environ Health Perspect
J4  - Environmental Health Perspectives
VL  - 124
IS  - 7
SP  - 1023
EP  - 1033
ER  - 


TY  - JOUR
A1  - Politi, R 
A1  - Rusyn, I 
A1  - Tropsha, A 
T1  - Prediction of binding affinity and efficacy of thyroid hormone receptor ligands using QSAR and structure-based modeling methods.
Y1  - 2014/10/1
N1  - R833825
N1  - R835166
JF  - TOXICOLOGY AND APPLIED PHARMACOLOGY
J1  - TOXICOL APPL PHARM
J2  - Toxicol.Appl.Pharmacol.
J3  - Toxicol Appl Pharmacol
J4  - Toxicology and Applied Pharmacology
VL  - 280
IS  - 1
SP  - 177
EP  - 189
ER  - 


TY  - JOUR
A1  - Reif, D M
A1  - Sypa, M 
A1  - Lock, E F
A1  - Wright, F A
A1  - Wilson, A 
A1  - Cathey, T 
A1  - Judson, R R
A1  - Rusyn, I 
T1  - ToxPi GUI: an interactive visualization tool for transparent integration of data from diverse sources of evidence.
Y1  - 2013/02/1
N1  - R835166
VL  - 29
IS  - 3
SP  - 402
EP  - 403
ER  - 


TY  - JOUR
A1  - Rusyn, I 
A1  - Sedykh, A 
A1  - Low, Y 
A1  - Guyton, K Z
A1  - Tropsha, A 
T1  - Predictive modeling of chemical hazard by integrating numerical descriptors of chemical structures and short-term toxicity assay data.
Y1  - 2012/05/
N1  - R833825
N1  - R835166
VL  - 127
IS  - 1
SP  - 1
EP  - 9
ER  - 


TY  - JOUR
A1  - Sirenko, O 
A1  - Cromwell, E F
A1  - Crittenden, C 
A1  - Wignall, J A
A1  - Wright, F A
A1  - Rusyn, I 
T1  - Assessment of beating parameters in human induced pluripotent stem cells enables quantitative <em>in vitro</em> screening for cardiotoxicity.
Y1  - 2013/12/15
N1  - R835166
VL  - 273
IS  - 3
SP  - 500
EP  - 507
ER  - 


TY  - JOUR
A1  - Sirenko, O 
A1  - Crittenden, C 
A1  - Callamaras, N 
A1  - Hesley, J 
A1  - Chen, Y W
A1  - Funes, C 
A1  - Rusyn, I 
A1  - Anson, B 
A1  - Cromwell, E F
T1  - Multiparameter in vitro assessment of compound effects on cardiomyocyte physiology using iPSC cells.
Y1  - 2013/01/
N1  - R835166
JF  - JOURNAL OF BIOMOLECULAR SCREENING
J1  - J BIOMOL SCREEN
VL  - 18
IS  - 1
SP  - 39
EP  - 53
ER  - 


TY  - JOUR
A1  - Sirenko, O 
A1  - Hesley, J 
A1  - Rusyn, I 
A1  - Cromwell, E F
T1  - High-content assays for hepatotoxicity using induced pluripotent stem cell-derived cells.
Y1  - 2014/01/
N1  - R835166
JF  - ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES
VL  - 12
IS  - 1
SP  - 43
EP  - 54
ER  - 


TY  - JOUR
A1  - Sirenko, O 
A1  - Hesley, J 
A1  - Rusyn, I 
A1  - Cromwell, E F
T1  - High-content high-throughput assays for characterizing the viability and morphology of human iPSC-derived neuronal cultures.
Y1  - 2014/11/
N1  - R835166
VL  - 12
IS  - 9-10
SP  - 536
EP  - 547
ER  - 


TY  - JOUR
A1  - Sirenko, O 
A1  - Grimm, F A
A1  - Ryan, K R
A1  - Iwata, Y 
A1  - Chiu, W A
A1  - Parham, F 
A1  - Wignall, J A
A1  - Anson, B 
A1  - Cromwell, E F
A1  - Behl, M 
A1  - Rusyn, I 
A1  - Tice, R R
T1  - <em>In vitro</em> cardiotoxicity assessment of environmental chemicals using an organotypic human induced pluripotent stem cell-derived model.
Y1  - 2017/05/1
N1  - R835802
N1  - R835166
VL  - 322
SP  - 60
EP  - 74
ER  - 


TY  - JOUR
A1  - Smith, M T
A1  - Guyton, K Z
A1  - Gibbons, C F
A1  - Fritz, J M
A1  - Portier, C J
A1  - Rusyn, I 
A1  - DeMarini, D M
A1  - Caldwell, J C
A1  - Kavlock, R J
A1  - Lambert, P F
A1  - Hecht, S S
A1  - Bucher, J R
A1  - Stewart, B W
A1  - Baan, R A
A1  - Cogliano, V J
A1  - Straif, K 
T1  - Key characteristics of carcinogens as a basis for organizing data on mechanisms of carcinogenesis.
Y1  - 2016/06/
N1  - R835166
VL  - 124
IS  - 6
SP  - 713
EP  - 721
ER  - 


TY  - JOUR
A1  - Wambaugh, J F
A1  - Wetmore, B A
A1  - Pearce, R 
A1  - Strope, C 
A1  - Goldsmith, R 
A1  - Sluka, J P
A1  - Sedykh, A 
A1  - Tropsha, A 
A1  - Bosgra, S 
A1  - Shah, I 
A1  - Judson, R 
A1  - Thomas, R S
A1  - Setzer, R W
T1  - Toxicokinetic triage for environmental chemicals.
Y1  - 2015/09/
N1  - R835001
N1  - R835166
JF  - TOXICOLOGICAL SCIENCES
J1  - TOXICOL SCI
J2  - Toxicol.Sci.
J3  - Toxicological Sciences
VL  - 147
IS  - 1
SP  - 55
EP  - 67
ER  - 


TY  - JOUR
A1  - Wignall, J A
A1  - Shapiro, A J
A1  - Wright, F A
A1  - Woodruff, T J
A1  - Chiu, W A
A1  - Guyton, K Z
A1  - Rusyn, I 
T1  - Standardizing benchmark dose calculations to improve science-based decisions in human health assessments.
Y1  - 2014/05/
N1  - R835166
VL  - 122
IS  - 5
SP  - 499
EP  - 505
ER  - 


TY  - JOUR
A1  - Wright, F A
A1  - Shabalin, A A
A1  - Rusyn, I 
T1  - Computational tools for discovery and interpretation of expression quantitative trait loci.
Y1  - 2012/02/
N1  - R833825
N1  - R835166
VL  - 13
IS  - 3
SP  - 343
EP  - 352
ER  - 


TY  - JOUR
A1  - Zeise, L 
A1  - Bois, F Y
A1  - Chiu, W A
A1  - Hattis, D 
A1  - Rusyn, I 
A1  - Guyton, K Z
T1  - Addressing human variability in next-generation human health risk assessments of environmental chemicals.
Y1  - 2013/01/
N1  - R835166
VL  - 121
IS  - 1
SP  - 23
EP  - 31
ER  - 


TY  - JOUR
A1  - Zhang, L 
A1  - Sedykh, A 
A1  - Tripathi, A 
A1  - Zhu, H 
A1  - Afantitis, A 
A1  - Mouchlis, V D
A1  - Melagraki, G 
A1  - Rusyn, I 
A1  - Tropsha, A 
T1  - Identification of putative estrogen receptor-mediated endocrine disrupting chemicals using QSAR- and structure-based virtual screening approaches.
Y1  - 2013/10/1
N1  - R833825
N1  - R835166
VL  - 272
IS  - 1
SP  - 67
EP  - 76
ER  -